Blood type is related to cancer risk. People at risk should be tested early

And the risk increased with each non-O allele added: compared with the OO genotype, the AO and AA subjects had a 33% and 61% increased risk of pancreatic cancer, respectively, and the BO and BB had a 45% and 142% increased risk, respectively.

Harvard University used the U.S. Nurses’ Health Study and Health Professionals Tracking Study database to study more than 100,000 people (including 316 pancreatic cancer patients) and found that compared with people with type O blood, people with type A, type AB, and type B blood were 32%, 51%, and 72% more likely to develop pancreatic cancer, respectively.

Another US study of 417 pancreatic cancer patients who underwent pancreatectomy found that non-O blood type increases the risk of pancreatic cancer, but does not affect the overall survival rate of patients. However, this study was limited to patients who underwent pancreatectomy, which only accounted for 20% of all pancreatic cancer patients. The rest of the patients could not undergo surgery.

Blood type A increases risk of gastric cancer

There are also many studies on the relationship between gastric cancer and blood type. A review study published in BMC Medicine in May this year showed that compared with non-A blood types, type A blood is associated with a higher risk of gastric cancer; compared with non-O blood types, type O blood is associated with a lower risk of gastric cancer. This result is similar to the results of an earlier study of 1,045 Chinese gastric cancer patients who underwent gastrectomy .

Another study of 1.09 million blood donors in Sweden and Denmark (including 688 gastric cancer patients) also showed that type A blood was associated with an increased risk of gastric cancer.

A Swedish study of 1.6 million blood donors (including 120,000 cancer cases) showed that type A blood was associated with an increased risk of pancreatic cancer, stomach cancer, pharyngeal cancer, and esophageal adenocarcinoma. Other studies have found that type B blood is associated with a higher risk of esophageal cancer compared with non-type B blood.

Blood type affects cancer development

Blood type not only affects the risk of cancer, but also the development of cancer. A study of 252 patients with hepatocellular carcinoma found that patients with type B blood had tumors that were more likely to invade blood vessels, and patients with RhD-positive blood had tumors that were more likely to appear in multiple locations, while patients with type AB blood had a lower chance of having tumors in multiple locations.